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Article

High-throughput microfluidic single-cell RT-qPCR.

Proceedings of the National Academy of Sciences of the United States of America - 23 Aug 2011

White Adam K, VanInsberghe Michael, Petriv Oleh I, Hamidi Mani, Sikorski Darek, Marra Marco A, Piret James, Aparicio Samuel, Hansen Carl L

Abstract excerpt

A long-sought milestone in microfluidics research has been the development of integrated technology for scalable analysis of transcription in single cells. Here we present a fully integrated microfluidic device capable of performing high-precision RT-qPCR measurements of gene expression from hundreds of single cells per run. Our device executes all steps of single-cell processing, including cell capture, cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21808033
DOI: 10.1073/pnas.1019446108
PMCID: PMC3161570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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