Article
Antiviral activity of virocidal peptide derived from NS5A against two different HCV genotypes: an in vitro study.
Journal of immunoassay & immunochemistry - 1 Jan 2015
El-Shenawy Reem, Tabll Ashraf, Bader El Din Noha G, El Abd Yasmine, Mashaly Mohamed, Abdel Malak Camelia A, Dawood Reham, El-Awady Mostafa
Abstract excerpt
This study aimed at assessment of the antiviral activity of an amphipathic α-helical peptide derived from the hepatitis C virus NS5A known as C5A virocidal peptide against different HCV genotypes. Two sources of HCV virus for in vitro study: HCV genotype 4 sera samples and JFH-1 infectious culture system genotype 2a were used. Several virocidal peptide concentrations were tested to determine the concentration...
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