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Article

The use of ovarian cancer cells from patients undergoing surgery to generate primary cultures capable of undergoing functional analysis.

PloS one - 1 Jan 2014

O Donnell Rachel L, McCormick Aiste, Mukhopadhyay Asima, Woodhouse Laura C, Moat Madeleine, Grundy Anna, Dixon Michelle, Kaufman Angelika, Soohoo San, Elattar Ahmed, Curtin Nicola J, Edmondson Richard J

Abstract excerpt

The use of cell lines or animal models has significant disadvantages when dealing with a set of heterogeneous diseases such as epithelial ovarian cancer. This has clinical relevance in that biomarkers developed using cell line or animal models are often not transferable to the clinical setting. In this study, we describe the development of a robust protocol for developing primary cultures of ovarian cancer which...

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Share to Carcinoma, Ovarian Epithelial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Drug Screening Assays, Antitumor

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Share to Neoplasms, Glandular and Epithelial

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Source

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Identifiers

PMID: 24603616
DOI: 10.1371/journal.pone.0090604
PMCID: PMC3948341

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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