LILRB2 interaction with HLA class I correlates with control of HIV-1 infection.

doi:10.1371/journal.pgen.1004196

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Article

LILRB2 interaction with HLA class I correlates with control of HIV-1 infection.

PLoS genetics - 1 Mar 2014

Bashirova Arman A, Martin-Gayo Enrique, Jones Des C, Qi Ying, Apps Richard, Gao Xiaojiang, Burke Patrick S, Taylor Craig J, Rogich Jerome, Wolinsky Steven, Bream Jay H, Duggal Priya, Hussain Shehnaz, Martinson Jeremy, Weintrob Amy, Kirk Gregory D, Fellay Jacques, Buchbinder Susan P, Goedert James J, Deeks Steven G, Pereyra Florencia, Trowsdale John, Lichterfeld Mathias, Telenti Amalio, Walker Bruce D, Allen Rachel L, Carrington Mary, Yu Xu G

Abstract excerpt

Natural progression of HIV-1 infection depends on genetic variation in the human major histocompatibility complex (MHC) class I locus, and the CD8+ T cell response is thought to be a primary mechanism of this effect. However, polymorphism within the MHC may also alter innate immune activity against human immunodeficiency virus type 1 (HIV-1) by changing interactions of human leukocyte antigen (HLA) class I...

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Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24603468
DOI: 10.1371/journal.pgen.1004196
PMCID: PMC3945438

Genes

LILRB2
LILRB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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