Article
Genetic disruption of the On visual pathway affects cortical orientation selectivity and contrast sensitivity in mice.
Journal of neurophysiology - 1 Jun 2014
Sarnaik Rashmi, Chen Hui, Liu Xiaorong, Cang Jianhua
Abstract excerpt
The retina signals stimulus contrast via parallel On and Off pathways and sends the information to higher visual centers. Here we study the role of the On pathway using mice that have null mutations in the On-specific GRM6 receptor in the retina (Pinto LH, Vitaterna MH, Shimomura K, Siepka SM, Balannik V, McDearmon EL, Omura C, Lumayag S, Invergo BM, Brandon M, Glawe B, Cantrell DR, Donald R, Inayat S, Olvera MA,...
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