Article
Integrative properties of retinal ganglion cell electrical responsiveness depend on neurotrophic support and genotype in the mouse.
Experimental eye research - 1 Apr 2016
Chou Tsung-Han, Feuer William J, Schwartz Odelia, Rojas Mario J, Roebber Jennifer K, Porciatti Vittorio
Abstract excerpt
Early stages of glaucoma and optic neuropathies are thought to show inner retina remodeling and functional changes of retinal ganglion cells (RGCs) before they die. To assess RGC functional plasticity, we investigated the contrast-gain control properties of the pattern electroretinogram (PERG), a sensitive measure of RGC function, as an index of spatio-temporal integration occurring in the inner retina circuitry...
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