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Article

Cell cycle-dependent regulation of Aurora kinase B mRNA by the Microprocessor complex.

Biochemical and biophysical research communications - 28 Mar 2014

Jung Eunsun, Seong Youngmo, Seo Jae Hong, Kwon Young-Soo, Song Hoseok

Abstract excerpt

Aurora kinase B regulates the segregation of chromosomes and the spindle checkpoint during mitosis. In this study, we showed that the Microprocessor complex, which is responsible for the processing of the primary transcripts during the generation of microRNAs, destabilizes the mRNA of Aurora kinase B in human cells. The Microprocessor-mediated cleavage kept Aurora kinase B at a low level and prevented premature...

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Identifiers

PMID: 24589731
DOI: 10.1016/j.bbrc.2014.02.104

Genes

DDX5
DDX17

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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