Article
Phenotypic modulation of smooth muscle cells by chemical and mechanical cues of electrospun tecophilic/gelatin nanofibers.
ACS applied materials & interfaces - 26 Mar 2014
Vatankhah Elham, Prabhakaran Molamma P, Semnani Dariush, Razavi Shahnaz, Zamani Maedeh, Ramakrishna Seeram
Abstract excerpt
The ability of mature smooth muscle cells (SMCs) to modulate their phenotype in response to environmental cues is a critical issue related to vascular diseases. A tissue engineered vascular graft shall promote the contractile phenotype of vascular SMCs. To this aim, Tecophilic/gelatin (TP/gel) was electrospun at different weight ratios of TP/gelatin (100:0, 70:30, 50:50, 30:70), leading to differences in...
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