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Article

Modulation of Smooth Muscle Cell Phenotype for Translation of Tissue-Engineered Vascular Grafts.

Tissue engineering. Part B, Reviews - 1 Oct 2023

Pineda-Castillo Sergio A, Acar Handan, Detamore Michael S, Holzapfel Gerhard A, Lee Chung-Hao

Abstract excerpt

Translation of small-diameter tissue-engineered vascular grafts (TEVGs) for the treatment of coronary artery disease (CAD) remains an unfulfilled promise. This is largely due to the limited integration of TEVGs into the native vascular wall-a process hampered by the insufficient smooth muscle cell (SMC) infiltration and extracellular matrix deposition, and low vasoactivity. These processes can be promoted through...

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Identifiers

PMID: 37166394
DOI: 10.1089/ten.TEB.2023.0006
PMCID: PMC10618830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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