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Article

The Ubiquitin Ligase ASB4 Promotes Trophoblast Differentiation through the Degradation of ID2

21 Feb 2014

Abstract excerpt

Vascularization of the placenta is a critical developmental process that ensures fetal viability. Although the vascular health of the placenta affects both maternal and fetal well being, relatively little is known about the early stages of placental vascular development. The ubiquitin ligase Ankyrin repeat, SOCS box-containing 4 (ASB4) promotes embryonic stem cell differentiation to vascular lineages and is...

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PMID: 24586788
DOI: 10.1371/journal.pone.0089451

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