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Article

Relationship between glycoprotein IIIa platelet receptor gene polymorphism and coronary artery disease.

Angiology - 1 Jan 2015

Verdoia Monica, Cassetti Ettore, Schaffer Alon, Barbieri Lucia, Giovine Gabriella Di, Nardin Matteo, Marino Paolo, Sinigaglia Fabiola, Luca Giuseppe De

Abstract excerpt

Glycoprotein IIb/IIIa (GP IIb/IIIa) is a key receptor for platelet aggregation and adhesion. We investigated whether a single-nucleotide polymorphism of GP IIIa subunit (Leu33Pro-PlA(1)/PlA(2) allele) is associated with the extent of coronary artery disease (CAD) in a consecutive cohort of 1518 patients undergoing coronary angiography. Significant CAD was defined as at least a stenosis >50% and severe CAD as left...

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Source

Identifiers

PMID: 24586027
DOI: 10.1177/0003319714524296

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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