Article
Association between the Pl(A) platelet glycoprotein GPIIIa polymorphism and extent of coronary artery disease.
International journal of cardiology - 1 Apr 2003
Gruchała Marcin, Ciećwierz Dariusz, Ochman Karolina, Targoński Radosław, Dubaniewicz Witold, Sobiczewski Wojciech, Wasag Bartosz, Drewla Piotr, Skarzynski Pawel, Romanowski Piotr, Limon Janusz, Rynkiewicz Andrzej
Abstract excerpt
BACKGROUND: The Pl(A2) allele of the gene encoding for GPIIIa subunit of the platelet membrane receptor glycoprotein (GP) IIb/IIIa has been suggested as a significant risk factor for thrombotic complications of coronary artery disease (CAD). The aim of the current investigation was to investigate the association between Pl(A) GPIIIa polymorphism and the extent of angiographically confirmed CAD in patients from...
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