Article
Association of the platelet glycoprotein IIIa PlA1/A2 gene polymorphism to coronary artery disease but not to nonfatal myocardial infarction in low risk patients.
Thrombosis and haemostasis - 1 Aug 1998
Gardemann A, Humme J, Stricker J, Nguyen Q D, Katz N, Philipp M, Tillmanns H, Hehrlein F W, Rau M, Haberbosch W
Abstract excerpt
BACKGROUND: The platelet membrane glycoprotein IIb/IIIa functions as a receptor for fibrinogen and von Willebrand factor during platelet aggregation. In a small case-control study, evidence has been presented that the PlA2 allele of the platelet glycoprotein GPIIIa PlA/A2 gene polymorphism might...
Topics
- Aged
- Alleles
- Case-Control Studies
- Coronary Angiography
- Coronary Disease
- Humans
- Male
- Middle Aged
- Myocardial Infarction
- Platelet Glycoprotein GPIIb-IIIa Complex
- Polymorphism, Genetic
- Risk Factors
- Survivors