Article
Association of single-nucleotide polymorphisms in a metabotropic glutamate receptor GRM3 gene subunit to alcohol-dependent male subjects.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000
Xia Yan, Wu Zheng, Ma Dongying, Tang Chunling, Liu Lei, Xin Feng, Zhu Daling, Hu Jian
Abstract excerpt
AIMS: The purpose of this study was to investigate the association between the metabotropic glutamate receptor 3 (GRM3) subunit gene and alcohol dependence by the single-nucleotide polymorphisms (SNPs). METHODS: Two hundred and forty-eight male alcohol-dependent patients and 235 male control subjects were recruited. Ten SNPs in the GRM3 region were studied, and genotyping of SNPs was performed by ligase detection...
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