Article
Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate levels and neurocognition in non-smoking, active alcoholics.
Behavioral and brain functions : BBF - 21 Aug 2012
Xia Yan, Ma Dongying, Hu Jian, Tang Chunling, Wu Zheng, Liu Lei, Xin Feng
Abstract excerpt
BACKGROUND: We studied the effects of single nucleotide polymorphisms (SNPs) in the metabotropic glutamate receptor 3 (GRM3) gene on brain N-acetylaspartate (NAA) concentrations and executive function (EF) skills in non-smoking, active alcoholics, and evaluated associations between these variables. METHODS: SNPs (rs6465084, rs1468412, and rs2299225) in GRM3 were genotyped in 49 male, non-smoking,...
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