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Article

Metabotropic glutamate receptor 3 is associated with heroin dependence but not depression or schizophrenia in a Chinese population.

PloS one - 1 Jan 2014

Jia Wei, Zhang Rui, Wu Bin, Dai Zun-xiao, Zhu Yong-sheng, Li Ping-ping, Zhu Feng

Abstract excerpt

Metabotropic glutamate receptor subtype 3 (mGluR3, encoded by GRM3) plays important roles in the pathophysiology of schizophrenia, depression, and drug dependence. GRM3 polymorphisms were reported to be associated with prefrontal activity, cognitive shifting, and memory capability in healthy subjects, as well as susceptibility to schizophrenia and depression. The goal of this study was to replicate the...

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Source

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Identifiers

PMID: 24498053
DOI: 10.1371/journal.pone.0087247
PMCID: PMC3909071

Genes

GRM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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