Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The association between functional HLA-G 14bp insertion/deletion and +3142 C>G polymorphisms and susceptibility to multiple sclerosis.

Immunology letters - 1 Dec 2016

Ben Fredj Nadia, Sakly Kaouthar, Bortolotti Daria, Aissi Mouna, Frih-Ayed Mahbouba, Rotola Antonella, Caselli Elisabetta, Cura Franscesca, Sakly Nabil, Aouni Mahjoub, Di Luca Dario, Rizzo Roberta

Abstract excerpt

We aimed to investigate two main polymorphisms in the 3' untranslated region (3'UTR) of the HLA-G gene [14bp insertion/deletion (INS/DEL) and +3142 C>G] and to assess their impact on the soluble HLA-G (sHLA-G) production in patients with multiple sclerosis (MS). This study included 60 patients with relasping-remitting (RR) MS and 112 healthy donors (HD). Mutations were identified by PCR and PCR-RFLP, and serum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Age of Onset

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Gene Frequency

Share to Haplotypes

Share to HLA-G Antigens

Share to Multiple Sclerosis

Share to Sequence Deletion

Source

Identifiers

PMID: 27771469
DOI: 10.1016/j.imlet.2016.10.006

Genes

INS
ADO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The association between functional HLA-G 14bp insertion/deletion and +3142 C>G polymorphisms and susceptibility to multiple sclerosis.PMID 27771469Read ↗

An investigation into the association between HLA-G 14 bp insertion/deletion polymorphism and multiple sclerosis susceptibility.Semantic proximity Read ↗

Role of HLA-G 14bp deletion/insertion and +3142C>G polymorphisms in the production of sHLA-G molecules in relapsing-remitting multiple sclerosis.Semantic proximity Read ↗

Association of HLA-G 3’UTR Polymorphisms with Soluble HLA-G Levels and Disease Activity in Patients with Rheumatoid Arthritis: A Case-Control StudySemantic proximity Read ↗

Association of the HLA-G gene +3142C>G polymorphism with systemic lupus erythematosus.Semantic proximity Read ↗

HLA-G 14 bp insertion/deletion polymorphism and its association with sHLA-G levels in Behçet's disease Tunisian patients.Semantic proximity Read ↗

HLA-G genotype and HLA-G expression in systemic lupus erythematosus: HLA-G as a putative susceptibility gene in systemic lupus erythematosus.Semantic proximity Read ↗

Polymorphic sites at the 3' untranslated region of the HLA-G gene are associated with differential hla-g soluble levels in the Brazilian and French population.Semantic proximity Read ↗

Genetic association between HLA-G 14-bp polymorphism and diseases: A systematic review and meta-analysis.Semantic proximity Read ↗

Lack of association between HLA-G 14-bp polymorphism and systemic lupus erythematosus in a Han Chinese population.Semantic proximity Read ↗

HLA-G +3142 polymorphism as a susceptibility marker in two rheumatoid arthritis populations in Brazil.Semantic proximity Read ↗

High-resolution melting curve analysis of polymorphisms within CD58, CD226, HLA-G genes and association with multiple sclerosis susceptibility in a subset of Iranian population: a case-control study.Semantic proximity Read ↗

Meta-analysis of the relationship between 14bp insertion/deletion polymorphism of HLA-G gene and susceptibility to systemic lupus erythematosus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.