Article
Argyrophilic grain pathology as a natural model of tau propagation.
Journal of Alzheimer's disease : JAD - 1 Jan 2014
Rábano Alberto, Rodal Izaskun, Cuadros Raquel, Calero Miguel, Hernández Félix, Ávila Jesús
Abstract excerpt
Argyrophilic grain disease (AGD) is a sporadic 4 R tauopathy that usually presents in combination with other sporadic tauopathies or with Alzheimer's disease (AD) pathology, and may contribute to dementia in older age patients. In previous studies, a detailed analysis of AGD pathology in the medial temporal lobe has been hampered by the common presence of concurrent AD changes. With the objective to assess the...
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