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Article

Staging of argyrophilic grains: an age-associated tauopathy.

Journal of neuropathology and experimental neurology - 1 Sept 2004

Saito Yuko, Ruberu Nyoka N, Sawabe Motoji, Arai Tomio, Tanaka Noriko, Kakuta Yukio, Yamanouchi Hiroshi, Murayama Shigeo

Abstract excerpt

We have reported that the ambient gyrus is the site with the greatest accumulation of argyrophilic grains (AGs) and that the degeneration of the ambient gyrus is responsible for dementia with grains. Here we analyzed 1,405 serial autopsy cases from 2 hospitals and detected AGs only in cases older than 56 years of age. The distribution of AGs followed a stereotypic regional pattern. Thus, we propose the following...

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Identifiers

PMID: 15453090
DOI: 10.1093/jnen/63.9.911

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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