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Article

Argyrophilic grain disease.

Brain : a journal of neurology - 1 Jun 2008

Ferrer Isidro, Santpere Gabriel, van Leeuwen Fred W

Abstract excerpt

Argyrophilic grain disease (AGD) is a common sporadic neurodegenerative disease of old age characterized by the presence of argyrophilic grains (AGs)--dendritic-derived appendages as revealed with the Golgi method--together with pre-tangle neurons in the limbic system, which accounts for about 5% of all demented cases. AGs and pre-tangle neurons contain hyperphosphorylated 4R tau. This is associated with a...

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Identifiers

PMID: 18234698
DOI: 10.1093/brain/awm305

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UBB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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