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Article

Diffuse form of argyrophilic grain disease: a new variant of four-repeat tauopathy different from limbic argyrophilic grain disease.

Acta neuropathologica - 1 Dec 2003

Maurage Claude-Alain, Sergeant Nicolas, Schraen-Maschke Susanna, Lebert Florence, Ruchoux Marie-Magdeleine, Sablonnière Bernard, Pasquier Florence, Delacourte André

Abstract excerpt

Argyrophilic grain disease (AGD) is characterized by the occurrence of argyrophilic grains and coiled bodies in brain tissue, mainly in limbic areas located in the temporal lobe. Recent biochemical data have shown that inclusions in AGD consist of aggregates of pathological microtubule-associated tau protein isoforms of 64/69 kDa. We report here a study on two AGD patients, belonging to a series of demented...

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PMID: 14517683
DOI: 10.1007/s00401-003-0762-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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