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Article

Are genes connected with homocysteine metabolism associated with bipolar disorder?

Neuropsychobiology - 1 Jan 2014

Permoda-Osip Agnieszka, Dmitrzak-Weglarz Monika, Hauser Joanna, Rybakowski Janusz K

Abstract excerpt

BACKGROUND: Increased levels of homocysteine have been observed in various psychiatric disorders, among them in schizophrenia, depression and bipolar mood disorder. Of the genes connected with homocysteine metabolism, some studies have found an association between polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene and bipolar disorder. The aim of this study was to investigate a possible...

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Share to Bipolar Disorder
Share to Cystathionine beta-Synthase
Share to Ferredoxin-NADP Reductase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MTRR gene

Share to Genetic Predisposition to Disease

Share to Genotyping Techniques

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 24577139
DOI: 10.1159/000358091

Genes

CBS
MTHFR
MTRR

Variants

rs1801133
rs1801133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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