Article
The 844ins68 polymorphism of the cystathionine beta-synthase gene is associated with schizophrenia.
Psychiatry research - 30 Dec 2009
Golimbet Vera, Korovaitseva Galina, Abramova Lilia, Kaleda Vasily
Abstract excerpt
A subtle genetic defect in homocysteine metabolism is thought to play an etiologic role in schizophrenia. Cystathionine-beta-synthase (CBS) is a key enzyme related to homocysteine levels. The aim of the present study was to search for association between the 844ins68 polymorphism of the CBS gene and schizophrenia in a large Russian sample using case-control and family-based designs. The sample comprised 1135...
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