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Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c

27 Feb 2014

Abstract excerpt

BACKGROUND: B7-H3, an immunoregulatory protein, is overexpressed in several cancers and is often associated with metastasis and poor prognosis. Here, our aim was to identify microRNAs (miRNAs) regulating B7-H3 and assess their potential prognostic implications in breast cancer. METHODS: MicroRNAs targeting B7-H3 were identified by transfecting two breast cancer cell lines with a library of 810 miRNA mimics and...

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PMID: 24577056
DOI: 10.1038/bjc.2014.113

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