Article
Genome-wide association scan of Dupuytren's disease.
The Journal of hand surgery - 1 Dec 2010
Ojwang Joshua O, Adrianto Indra, Gray-McGuire Courtney, Nath Swapan K, Sun Celi, Kaufman Kenneth M, Harley John B, Rayan Ghazi M
Abstract excerpt
PURPOSE: Dupuytren's disease (DD) has a strong genetic component that is suggested by population studies and family clustering. Genetic studies have yet to identify the gene(s) involved in DD. The purpose of this study was to identify regions of the entire genome (chromosomes 1-23) associated with the disease by performing a genome-wide association scan on DD patients and controls. METHODS: We isolated genomic...
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