Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dupuytren diathesis and genetic risk.

The Journal of hand surgery - 1 Oct 2012

Dolmans Guido H, de Bock Geertruida H, Werker Paul M

Abstract excerpt

PURPOSE: Dupuytren disease (DD) is a benign fibrosing disorder of the hand and fingers. Recently, we identified 9 single nucleotide polymorphisms (SNPs) associated with DD in a genome-wide association study. These SNPs can be used to calculate a genetic risk score for DD. The aim of this study was to test whether certain clinical characteristics (including the DD diathesis features) of patients with DD are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Dupuytren Contracture
Share to Dupuytren's Contracture and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroma

Share to Genetic Predisposition to Disease

Share to Logistic Models

Share to Polymorphism, Single Nucleotide

Share to Risk Assessment

Source

Identifiers

PMID: 23021175
DOI: 10.1016/j.jhsa.2012.07.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dupuytren diathesis and genetic risk.PMID 23021175Read ↗

A meta-analysis of genome-wide association studies in 614,243 individuals identifies 59 novel susceptibility loci underlying Dupuytren’s contractureSemantic proximity Read ↗

A genome-wide association meta-analysis implicates Hedgehog and Notch signaling in Dupuytren's disease.Semantic proximity Read ↗

The heritability of Dupuytren's disease: familial aggregation and its clinical significance.Semantic proximity Read ↗

Molecular genetics of Dupuytren’s contractureSemantic proximity Read ↗

The importance of genetic susceptibility in Dupuytren's disease.Semantic proximity Read ↗

A Genome-Wide Association Study and Rare Variant Analysis for Dupuytren Disease in a North American Population.Semantic proximity Read ↗

Genome-wide association scan of Dupuytren's disease.Semantic proximity Read ↗

Polygenic Risk Associations with Clinical Characteristics and Recurrence of Dupuytren Disease.Semantic proximity Read ↗

SNPs previously associated with Dupuytren's disease replicated in a North American cohort.Semantic proximity Read ↗

Genome-Wide Analysis Using Exon Arrays Demonstrates an Important Role for Expression of Extra-Cellular Matrix, Fibrotic Control and Tissue Remodelling Genes in Dupuytren's DiseaseSemantic proximity Read ↗

A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis.Semantic proximity Read ↗

GENETICS OF DUPUYTREN’S DISEASESemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.