Article
Exceptional expansion and conservation of a CT-repeat complex in the core promoter of PAXBP1 in primates.
American journal of primatology - 1 Aug 2014
Mohammadparast Saeid, Bayat Hadi, Biglarian Akbar, Ohadi Mina
Abstract excerpt
Adaptive evolution may be linked with the genomic distribution and function of short tandem repeats (STRs). Proximity of the core promoter STRs to the +1 transcription start site (TSS), and their mutable nature are characteristics that highlight those STRs as a novel source of interspecies variation. The PAXBP1 gene (alternatively known as GCFC1) core promoter contains the longest STR identified in a Homo sapiens...
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