Article
More single-nucleotide mutations surround small insertions than small deletions in primates.
Human mutation - 1 Jul 2012
Huang Shengfeng, Yu Ting, Chen Zelin, Yuan Shaochun, Chen Shangwu, Xu Anlong
Abstract excerpt
Early studies have shown that single-nucleotide mutation rates increase close to insertions and deletions, but it is not fully understood how natural selection shapes genome-wide patterns of indels and their nearby single-nucleotide mutations. In this study, we find that, in primates, more single-nucleotide mutations surround small insertions than small deletions. This pattern affects <150 base pair (bp)...
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