Article
A genome-wide screen for noncoding elements important in primate evolution.
BMC evolutionary biology - 23 Jan 2008
Bush Eliot C, Lahn Bruce T
Abstract excerpt
BACKGROUND: A major goal in the study of human evolution is to identify key genetic changes which occurred over the course of primate evolution. According to one school of thought, many such changes are likely to be found in noncoding sequence. An approach to identifying these involves comparing multiple genomes to identify conserved regions with an accelerated substitution rate in a particular lineage. Such...
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