Article
Evolutionary pattern of protein architecture in mammal and fruit fly genomes.
Genomics - 1 Jan 2009
Yang Haiwang, Wu Ying, Feng Jing, Yang Sihai, Tian Dacheng
Abstract excerpt
Mutations, which can alter amino acid constitution, contribute greatly to protein evolution. However, little is reported of their pattern during protein structural evolution. We investigated the distribution of non-synonymous single nucleotide polymorphisms (nsSNPs) and insertions/deletions (indels) along mammal and fruit fly proteins. We found the nsSNPs (and d(N)) and indels increased in protein boundary...
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