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Article

Prevalence of multinucleotide replacements in evolution of primates and Drosophila.

Molecular biology and evolution - 1 Jun 2013

Terekhanova Nadezhda V, Bazykin Georgii A, Neverov Alexey, Kondrashov Alexey S, Seplyarskiy Vladimir B

Abstract excerpt

Evolution of sequences mostly involves independent changes at different sites. However, substitutions at neighboring sites may co-occur as multinucleotide replacement events (MNRs). Here, we compare noncoding sequences of several species of primates, and of three species of Drosophila fruit flies, in a phylogenetic analysis of the replacements that occurred between species at nearby nucleotide sites. Both in...

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PMID: 23447710
DOI: 10.1093/molbev/mst036
PMCID: PMC3649671

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