Article
An initial assessment of correlations between host- and virus-related factors affecting analogues antiviral therapy in HBV chronically infected patients.
Medical science monitor : international medical journal of experimental and clinical research - 26 Feb 2014
Stalke Piotr, Rybicka Magda, Wróblewska Anna, Dreczewski Marcin, Stracewska Ewa, Smiatacz Tomasz, Bielawski Krzysztof Piotr
Abstract excerpt
BACKGROUND: Success in treating hepatitis B virus (HBV) infection with nucleoside analogues drugs is limited by the emergence of drug-resistant viral strains upon prolonged therapy. In addition to mutation patterns in the viral polymerase gene, host factors are assumed to contribute to failure of treatment in chronic HBV infections. The aim of this study was to analyze the correlation between efficacy of...
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