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Article

Antiviral therapies: focus on hepatitis B reverse transcriptase.

The international journal of biochemistry & cell biology - 1 Jul 2012

Michailidis Eleftherios, Kirby Karen A, Hachiya Atsuko, Yoo Wangdon, Hong Sun Pyo, Kim Soo-Ok, Folk William R, Sarafianos Stefan G

Abstract excerpt

Hepatitis B virus (HBV) is the etiologic agent of mankind's most serious liver disease. While the availability of a vaccine has reduced the number of new HBV infections, the vaccine does not benefit the approximately 350 million people already chronically infected by the virus. Most of the drugs approved by the FDA for the treatment of hepatitis B target the reverse transcriptase (RT or P gene product) and are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Drug Resistance, Viral

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Source

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Identifiers

PMID: 22531713
DOI: 10.1016/j.biocel.2012.04.006
PMCID: PMC3522522

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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