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Article

Mutations in Pol gene of hepatitis B virus in patients with chronic hepatitis B before and after therapy with nucleoside/nucleotide analogues.

Acta virologica - 1 Jan 2014

Januszkiewicz-Lewandowska D, Rucka A, Kowala-Piaskowska A, Bereszynska I, Mozer-Lisewska I, Zajac-Spychala O, Wysocki J, Nowak J

Abstract excerpt

Chronic hepatitis B (CHB) is one of the most common infections worldwide. Currently approved treatments of CHB include nucleoside/nucleotide analogues (NAs). However, long-term NA therapy is associated with accumulation of resistant mutations within the hepatitis B virus (HBV) polymerase gene. The incidence of naturally occurring HBV mutations leading to primary antiviral resistance has not been fully elucidated...

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Identifiers

PMID: 24957725
DOI: 10.4149/av_2014_02_185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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