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Article

A Lack of Association between Vitamin D Receptor Gene Polymorphisms with Colorectal Cancer: A Comprehensive Meta-Analysis and Power Assessment.

Critical reviews in eukaryotic gene expression - 1 Jan 2026

Anilkumar Anu Shibi, Thomas Sheena Mariam, Veerabathiran Ramakrishnan

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) remains a major global health burden, and genetic factors such as vitamin D receptor (VDR) polymorphisms have been implicated in its pathogenesis. However, the translational relevance of these variants in clinical risk stratification remains unclear. METHODS: We conducted a comprehensive meta-analysis of case-control studies assessing the association between four common VDR...

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Case-Control Studies
Colorectal Neoplasms
VDR gene
Genetic Predisposition to Disease
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Calcitriol

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PMID: 41824933
DOI: 10.1615/CritRevEukaryotGeneExpr.2025062255

Genes

VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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