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Article

Lack of Association Between BsmI and FokI Polymorphisms of the VDR Gene and Sporadic Colorectal Cancer in a Romanian Cohort-A Preliminary Study.

Current oncology (Toronto, Ont.) - 21 Oct 2024

Petre-Mandache Bianca, Burada Emilia, Cucu Mihai Gabriel, Atasie Diter, Riza Anca-Lelia, Streață Ioana, Mitruț Radu, Pleșea Răzvan, Dobrescu Amelia, Pîrvu Andrei, Popescu-Hobeanu Gabriela, Mitruț Paul, Burada Florin

Abstract excerpt

Colorectal cancer (CRC) is a major public health problem worldwide, currently ranking third in cancer incidence and second in mortality. Multiple genes and environmental factors have been involved in the complex and multifactorial process of CRC carcinogenesis. VDR is an intracellular hormone receptor expressed in both normal epithelial and cancer colon cells at various levels. Several VDR gene polymorphisms,...

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Aged
Case-Control Studies
Cohort Studies
Colorectal Neoplasms
Deoxyribonucleases, Type II Site-Specific

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Receptors, Calcitriol

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Open in PubMed Open full text

Identifiers

PMID: 39451780
DOI: 10.3390/curroncol31100476
PMCID: PMC11505952

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