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Article

SNP rs2057482 in HIF1A gene predicts clinical outcome of aggressive hepatocellular carcinoma patients after surgery.

Scientific reports - 26 Jun 2015

Guo Xu, Li Deyang, Chen Yibing, An Jiaze, Wang Kan, Xu Zhuding, Chen Zhinan, Xing Jinliang

Abstract excerpt

Hypoxia-inducible factor 1α (HIF-1α) plays an important role in tumor growth and metastasis. Genetic variations of HIF1A gene have been shown to influence the developing risk and prognosis in many types of human malignancies. However, their association with clinical outcomes of hepatocellular carcinoma (HCC) patients remains unclear. To investigate the predictive role of single nucleotide polymorphisms (SNPs) in...

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Identifiers

PMID: 26115041
DOI: 10.1038/srep11846
PMCID: PMC4481773

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AFP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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