Article
A replication study of the association between rheumatoid arthritis and deletion of the late cornified envelope genes LCE3B and LCE3C.
PloS one - 1 Jan 2012
Bergboer Judith G M, Umićević-Mirkov Maša, Fransen Jaap, den Heijer Martin, Franke Barbara, van Riel Piet L C M, Schalkwijk Joost, Coenen Marieke J H
Abstract excerpt
OBJECTIVE: Two recent studies, in a Spanish and a Chinese population, point to an association between rheumatoid arthritis (RA) risk and the deletion of the Late Cornified Envelope (LCE) 3B and 3C genes (LCE3C_LCE3B-del), a known risk factor for psoriasis. We aimed to replicate these studies in a large Dutch cohort. METHODS: 1039 RA cases and 759 controls were genotyped for LCE3C_LCE3B-del. Association analysis...
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