Article
HCS-Neurons: identifying phenotypic changes in multi-neuron images upon drug treatments of high-content screening.
BMC bioinformatics - 1 Jan 2013
Charoenkwan Phasit, Hwang Eric, Cutler Robert W, Lee Hua-Chin, Ko Li-Wei, Huang Hui-Ling, Ho Shinn-Ying
Abstract excerpt
BACKGROUND: High-content screening (HCS) has become a powerful tool for drug discovery. However, the discovery of drugs targeting neurons is still hampered by the inability to accurately identify and quantify the phenotypic changes of multiple neurons in a single image (named multi-neuron image)...
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