Article
[Study on the effect of deficient ERCC2/XPD gene on the repair of DNA damage induced by UVC in CHO cell line].
Wei sheng yan jiu = Journal of hygiene research - 1 Jan 2014
Guan Yangyang, Xiao Sha, Li Dandan, Xue Ping, Zhang Guopei, Liu Qiufang, Jin Cuihong, Yang Jinghua, Wu Shengwen, Lu Xiaobo
Abstract excerpt
OBJECTIVE: To explore the function of ERCC2/XPD in the repair of DNA damage induced by UVC. METHODS: Chinese hamster ovary (CHO) cell line including AA8 (wild-type) and UV5 (mutant type, ERCC2/XPD defective), was selected as a cell control model. The cell inhibition rate of AA8 and UV5 after UVC treatment was estimated by MTT assay, and DNA repair capacity to difference irradiation intensity of UVC in cells after...
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