[Explore the genotype characteristics of DNA repair enzyme XRCC1 and XPD in the lens epithelium associated with free radical level in the age-related cataract patients].

Abstract excerpt

OBJECTIVE: To explore the genotype characteristics of DNA repair enzyme XPD-751 and XRCC1-399 in the lens epithelium of cataract patients, and difference in free radical level. METHODS: The genome DNA was extracted from respective lens epithelium of 30 cataract patients, their peripheral blood and 12 normal control's peripheral blood by using a Genomic DNA kit, and the polymorphisms of DNA repair enzymes XPD-751...

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