Article
[Study on association between ERCC2/XPD single nucleotide polymorphisms and DNA adducts damage induced by B[a]P in vitro].
Wei sheng yan jiu = Journal of hygiene research - 1 Jan 2013
Liu Yanhua, Yu Tao, Xiao Sha, Guan Yangyang, Li Dandan, Jin Cuihong, Liu Qiufang, Yang Jinghua, Wu Shengwen, Lu Xiaobo
Abstract excerpt
OBJECTIVE: To evaluate the association between DNA damage repair capacity induced by environment carcinogen benzo[a] pyrene (B [a] P) and ERCC2/XPD single nucleotide polymorphisms(SNP). METHODS: 8 ml peripheral bloods of 282 healthy ethnic Han people from Liao-ning province were collected, isolated lymphocytes and extracted DNA. The genotypes of ERCC2/XPD Lys751 Gln (rs13181), Asp312Asn (rs1799793), Arg156Arg...
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