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Article

Combined Analysis of Phenotypic and Target-Based Screening in Assay Networks.

Journal of biomolecular screening - 1 Jun 2014

Swamidass S Joshua, Schillebeeckx Constantino N, Matlock Matthew, Hurle Mark R, Agarwal Pankaj

Abstract excerpt

Small-molecule screens are an integral part of drug discovery. Public domain data in PubChem alone represent more than 158 million measurements, 1.2 million molecules, and 4300 assays. We conducted a global analysis of these data, building a network of assays and connecting the assays if they shared nonpromiscuous active molecules. This network spans both phenotypic and target-based screens, recapitulates known...

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Source

Identifiers

PMID: 24563424
DOI: 10.1177/1087057114523068

Genes

ALOX15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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