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Article

Unveiling new biological relationships using shared hits of chemical screening assay pairs.

Bioinformatics (Oxford, England) - 1 Sept 2014

Liu Xueping, Campillos Monica

Abstract excerpt

MOTIVATION: Although the integration and analysis of the activity of small molecules across multiple chemical screens is a common approach to determine the specificity and toxicity of hits, the suitability of these approaches to reveal novel biological information is less explored. Here, we test the hypothesis that assays sharing selective hits are biologically related. RESULTS: We annotated the biological...

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PMID: 25161250
DOI: 10.1093/bioinformatics/btu468
PMCID: PMC4147921

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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