Article
Clinical Neuropathology practice news 2-2014: ATRX, a new candidate biomarker in gliomas.
Clinical neuropathology - 1 Jan 2000
Haberler Christine, Wöhrer Adelheid
Abstract excerpt
Genome-wide molecular approaches have substantially elucidated molecular alterations and pathways involved in the oncogenesis of brain tumors. In gliomas, several molecular biomarkers including IDH mutation, 1p/19q co-deletion, and MGMT promotor methylation status have been introduced into neuropathological practice. Recently, mutations of the ATRX gene have been found in various subtypes and grades of gliomas...
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