Article
Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type.
BMC genomics - 21 Feb 2014
Smith Alicia K, Kilaru Varun, Kocak Mehmet, Almli Lynn M, Mercer Kristina B, Ressler Kerry J, Tylavsky Frances A, Conneely Karen N
Abstract excerpt
BACKGROUND: Individual genotypes at specific loci can result in different patterns of DNA methylation. These methylation quantitative trait loci (meQTLs) influence methylation across extended genomic regions and may underlie direct SNP associations or gene-environment interactions. We hypothesized that the detection of meQTLs varies with ancestral population, developmental stage, and tissue type. We explored this...
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