Article
CxxC-ZF domain is needed for KDM2A to demethylate histone in rDNA promoter in response to starvation.
Cell structure and function - 1 Jan 2014
Tanaka Yuji, Umata Toshiyuki, Okamoto Kengo, Obuse Chikashi, Tsuneoka Makoto
Abstract excerpt
The transcription of ribosomal RNA genes (rDNA) is a rate-limiting step in ribosome biogenesis and changes profoundly in response to environmental conditions. Recently we reported that JmjC demethylase KDM2A reduces rDNA transcription on starvation, with accompanying demethylation of dimethylated...
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