Article
Interactions between collagen gene variants and risk of anterior cruciate ligament rupture.
European journal of sport science - 1 Jan 2015
O'Connell Kevin, Knight Hayley, Ficek Krzysztof, Leonska-Duniec Agata, Maciejewska-Karlowska Agnieszka, Sawczuk Marek, Stepien-Slodkowska Marta, O'Cuinneagain Dion, van der Merwe Willem, Posthumus Michael, Cieszczyk Pawel, Collins Malcolm
Abstract excerpt
The COL5A1 and COL12A1 variants are independently associated with modulating the risk of anterior cruciate ligament (ACL) rupture in females. The objective of this study was to further investigate if COL3A1 and COL6A1 variants independently, as well as, collagen gene-gene interactions, modulate ACL rupture risk. Three hundred and thirty-three South African (SA, n = 242) and Polish (PL, n = 91) participants with...
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