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Article

Association between COX-2 rs 6681231 genotype and interleukin-6 in periodontal connective tissue. A pilot study.

PloS one - 1 Jan 2014

Mesa Francisco, O'Valle Francisco, Rizzo Manfredi, Cappello Francesco, Donos Nikos, Parkar Mohamed, Chaudhary Navidah, Carini Francesco, Muñoz Ricardo, Nibali Luigi

Abstract excerpt

OBJECTIVES: The aim of this pilot study was to investigate associations between IL-6 and COX-2 expression in gingival biopsies and both clinical diagnosis and genotypes in the IL-6 and COX-2 genes. DESIGN: A case-control study included 41 gingival biopsies obtained from Caucasian patients grouped according to clinical diagnosis of gingival health (n = 10), gingivitis (n = 15) or chronic periodontitis (n = 16)....

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Source

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Identifiers

PMID: 24551049
DOI: 10.1371/journal.pone.0087023
PMCID: PMC3923747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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