COX-2 gene polymorphisms and risk of chronic periodontitis: a case-control study and meta-analysis.

doi:10.1111/odi.12203

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Article

COX-2 gene polymorphisms and risk of chronic periodontitis: a case-control study and meta-analysis.

Oral diseases - 1 Jan 2015

Prakash G, Umar M, Ajay S, Bali D, Upadhyay R, Gupta K K, Dixit J, Mittal B

Abstract excerpt

OBJECTIVE: Cyclooxygenase-2 (COX-2) enzyme is a major mediator of inflammation in periodontitis, leading to loss of gingival tissues and alveolar bone supporting the teeth. Previous studies have explored the role of COX-2 polymorphisms with the risk of periodontitis in different ethnic groups; however, findings are inconsistent. So, we aimed to investigate the association of COX-2 polymorphisms (rs20417,...

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PMID: 24267395
DOI: 10.1111/odi.12203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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